Fatty Liver

Fatty liver, as the name suggests, is a condition that occurs as a result of excessive accumulation of fat in the liver cells. It occurs with the same frequency in men and women. Normally, a small amount of fat can be found in liver cells and this does not cause any damage.

However, excess fat causes functional and structural changes in the liver. Fatty liver can be accompanied by diseases that go with inflammation (inflammation) in the liver, or it can lead to inflammation in the liver itself. As a result, liver cells (hepatocytes) damage and liver fibrosis develops. As necrosis (cell destruction and death) in the liver progresses, the event develops into liver cirrhosis and can become a serious condition. Therefore, patients with advanced fatty liver should be carefully evaluated and followed closely.

What Is Liver Attachment-Related Hepatitis (Steatohepatitis)?

Benign hepatosteatosis (benign fatty liver) refers to the accumulation of lipid (fat) droplets within liver cells (hepatocytes). The term hepatitis is a term denoting inflammation (inflammation) of liver cells and the resulting cell damage. Steatohepatitis (steatosis = adiposity, steatohepatitis = fatty inflammation) means inflammation caused by the accumulation of fat in the liver. Although rare, benign hepatosteatosis can turn into steatohepatitis (8-20%). Likewise, fatty liver and inflammation of the liver as a result of alcohol use are also called alcoholic hepatitis.

Since steatohepatitis can be seen in people who have never consumed alcohol, it is called non-alcoholic fatty hepatitis (non-alcoholic – steato – hepatitis, NASH). NASH is a term used to describe the clinical syndrome in patients with liver biopsy found to be fatty and inflammatory and no other cause of liver disease has been demonstrated.

Steatohepatitis can lead to severe liver damage and cirrhosis. It is known that 10-20% of patients with NASH may develop liver cirrhosis. Studies have shown that steatohepatitis can develop in people who are overweight, lose weight quickly, use estrogen hormone, and diabetics whose blood sugar is not under control.

What are the Causes of Fatty Liver?

The liver plays an important role in the metabolism and breakdown of fats in our body. Disruptions during the metabolism of fats in the liver can cause fat accumulation in the liver. Metabolism or secretion of fats in the liver is closely related to the capacity of circulating fatty acids to be retained by fat stores in other tissues. Fat secretion from the liver is impaired in hepatic steatosis. When the amount of carbohydrates coming to it increases, the liver spends the excess carbohydrates by converting them to fatty acids. Fatty acids released from the liver but not metabolized are reesterified in the liver and triglycerides are formed again. Excessive intake of carbohydrates in the diet leads to the accumulation of fat in the liver.

The most common form of fatty liver is the type that occurs during the course of other diseases. The most well-known of these is obesity. Fatty liver is detected in 2/3 of people whose body weight is more than 10% of normal. Apart from this, diabetes (especially type 2 diabetes mellitus), hypertriglyceridemia (high triglyceride levels in the blood) and excessive alcohol use are other common conditions that can lead to fatty liver. High blood lipid cholesterol alone is not a risk factor for fatty liver. Excessive use of vitamin A, long-term intravenous nutrition, rapid weight loss and corticosteroids, etc. Long-term use of drugs can cause fatty liver. Although it seems logical that a diet with fatty foods can cause fatty liver, this type of diet does not cause fatty liver unless it leads to excessive weight gain and elevated blood triglyceride levels.

Fatty Liver Treatment

Fatty liver is a disease that usually resolves and regresses when the underlying causes are eliminated. Treatment is usually done according to the cause of lubrication. For example; such as losing excess weight (obesity treatment), lowering high blood triglyceride levels, controlling diabetes, and cessation of alcohol use. The coexistence of obesity (being overweight) with high blood triglyceride levels and diabetes can make the condition more serious. Patients who cannot lose weight with exercise and diet programs should be assisted with other methods, such as the insertion of a weakening gastric balloon (see attenuating gastric balloon). Liver transplantation is rarely needed in steatohepatitis.

How is Fatty Liver Treated?

Treatment of fatty liver depends on the cause. An overweight patient must lose weight and move. i have diabetes